Žmogaus smegenų sandara tokia sudėtinga, kad mokslas taip ir neišsiaiškino iki galo, kaip gi visa tai veikia. Tačiau visiems žinoma, kad netgi menkiausi pažeidimai ir šokai gali pridaryti smegenims didžiulės žalos. Tačiau kiekviena taisyklė turi išimčių, ir medicinos literatūroje esama liudijimų apie smarkius smegenų pažeidimus, kurie visiškai nepakenkė normaliam gyvenimui.
Žurnalas „Medikal pres of Niujork“ 1888 metais rašė apie vyrą, kuris prarado ketvirtadalį smegenų, kai jį užspaudė tarp tilto ir laivo, kuriame jis tarnavo. Tilto sija nupjovė dalį kaukolės, gydytojai užsiuvo žaizdą ir konstatavo, kad sužeistasis prarado didelę dalį smegenų medžiagos bei kraujo, ir gyvens jis neilgai. Tačiau kai tik jis atsipeikėjo, iškart ėmė kalbėti ir netgi pats apsirengė, tarsi nieko nebūtų nutikę. Ir jeigu nekreipti dėmesio į nedidelį svaigulį, jis galėjo pasigirti puikiausia sveikata, kol po 26 metų nebuvo dalinai paralyžuotas.
Kitas atvejis. Kūdikis, gimęs 1935 metais Niujorko šventojo Vincento ligoninėje 26 dienas elgėsi kaip normalus vaikas: rėkė, valgė, judėjo. Išgyveno jis neilgai. Tik po skrodimo gydytojai pamatė, kad pas jį apskritai nebuvo smegenų.
1953 metais daktaras Janas Briuelis ir daktaras Džordžas Elbis Amerikos psichologų asociacijoje padarė pranešimą apie vieną jų operuotą vyriškį. Nors jiedu visiškai pašalino jam dešinį smegenų pusrutulį, vyriškis išgyveno. Be to, operacija, kaip teko įsitikinti nustebę gydytojai, praktiškai nepadarė jokios neigiamos įtakos intelektualiems paciento sugebėjimams.
Brazilų gydytojai Augustinas Ituriša ir Nikolas Ortisas paliudijo apie tokį atvejį. Kalbėdamas antropologų draugijoje, Ituriša papasakojo apie savo keturiolikmetį pacientą, kuris kentė didelius galvos skusmus. Iš pradžių gydytojai aiškino ligą smegenų abscesu. Berniukui mirus, skrodimo metu buvo nustatyta, kad jo smegenų audiniai visiškai atsiskyrė nuo kaukolės, kas turėjo baigtis žaibiška mirtimi. Tačiau berniukas dar kurį laiką gyveno, protavo ir buvo visiškai normalus.
Dar vieną įdomų atvejį turėjo vokiečių smegenų ekspertas Hufelandas. Darydamas skrodimą vyriškiui, kuris iki pat mirties momento buvo visiškai sąmoningas, ekspertas išvis nerado smegenų. Vietoje jų buvo tik apie 300 gramų vandens.
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